Nonetheless, the same focus of Acquire but not other CB1R agonists, raises intracellular Ca2+ focus by means of Gq/11 protein in transfected HEK-293 cells and cultured hippocampal neurons with endogenous receptor expression [93]. Moreover, in mice hippocampal slices, CB1R expressed in astrocytes is coupled to Gq/eleven, increases intracellular Ca2+ concentrations https://carcrashcompensation65184.blogoscience.com/39336268/facts-about-endocannabinoid-system-revealed