Pentobarbital improves toxicity of buprenorphine, very long-acting injection by pharmacodynamic synergism. Modify Therapy/Keep track of Intently. Coadministration of buprenorphine and benzodiazepines or other CNS depressants increases hazard of adverse reactions which include overdose, respiratory depression, and Dying. Cessation of benzodiazepines or other CNS depressants is most wel... https://frankh557str7.mycoolwiki.com/user