Background: Erythema multiforme (EM) is an acute cutaneous eruption often associated with infections and more rarely with drugs. This review aimed to evaluate the association between erythema multiforme and coronavirus disease 2019 (COVID-19). Methods: A systematic search of PubMed/MEDLINE. Scimago Scopus. https://www.ealisboa.com/limited-value-AXYS-Valhalla-Pen-must-buy/