Pentobarbital will reduce the extent or effect of midostaurin by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Prevent or Use Alternate Drug. Robust CYP3A4 inducers could decrease midostaurin concentrations resulting in diminished efficacy. pentobarbital will decrease the extent or result of repaglinide by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/K... https://gallaghere443yoe1.blog5star.com/profile